Objectives: To identify the main risk factors of vascular cognitive impairment\nin patients with acute cerebral infarction by Meta-analysis, and provide references\nfor the effective prevention of the cognitive impairment in stroke patients.\nMethods: To retrieve the observational research literatures that refer to\nthe risk factors of vascular cognitive impairment in patients with ischemic\nstroke, which are published on China National Knowledge Infrastructure\n(CNKI), Wanfang and Weipu Chinese databases. The screening and data extraction\nof these literatures are independently completed by two researchers,\nwho also give the quality evaluation of the literatures according to the evaluation\ncriterion of the Australian JBI Evidence-Based Health Care Center. Then,\nMeta-analysis is conducted by using Revman5.3 software. Results: There are\ntwenty-eight articles selected from 1507 literatures, with a total of 10,711 cases\nand 50 risk factors included. Among them, there are combined effects of\nten factors which have statistical significance, such as infarction area, alcohol\nconsumption, smoking, hyper homocysteinemia, hypertension, diabetes mellitus,\nage, history of cerebral infarction, hyperlipoidemia and education level.\nThe relational merging OR value and 95% CI between the type-variable factors\nand cognitive impairment are 3.25.........
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